Research publications

2025

• Ferla R, Pugni E, Lupo M, et al. Retinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models. Sci Adv. 2025;11(13):eadt9354. doi:10.1126/sciadv.adt9354
• Arnold LC, Sout TAE, Beitsma MM, Deelen CC, Rizzo M, Leemans B, Galli C, Colleoni S, Lazzari G, Barandalla M, Claes A. Marked blastomere herniation is the only post-thaw morphological characteristic associated with a reduced pregnancy rate for in vitro produced equine blastocysts. Theriogenology. 2025 Mar 15:235:1-8.

2024

• Golia MT, Frigerio R, Pucci S, et al. Changes in glial cell activation and extracellular vesicles production precede the onset of disease symptoms in transgenic hSOD1G93A pigs. Exp Neurol. 2024:374:114716.
• Naso F, Gandaglia A, Sturaro G, Galli C, Melder RJ. The α-Gal KO Mouse Animal Model is a Reliable and Predictive Tool for the Immune-Mediated Calcification Assessment of Heart Valve Bioprostheses. Front Biosci (Landmark Ed). 2024;29(5):181.
• Viklicky O, Slatinska J, Janousek L, et al. First-in-human Study With LIS1, a Next-generation Porcine Low Immunogenicity Antilymphocyte Immunoglobulin in Kidney Transplantation. Transplantation. 2024;108(7): e139-e147.
• Biasetti P, Mercugliano E, Schrade L, Spiriti MM, Göritz F, Holtze S, Seet S, Galli C, Stejskal J, Colleoni S, Čižmár D, Simone R, Hildebrandt TB, de Mori B. Ethical assessment of genome resource banking (GRB) in wildlife conservation. Cryobiology. 2024 Aug 22:104956. doi: 10.1016/j.cryobiol.2024.104956. Epub ahead of print. PMID: 39181526.
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2023

• Rousse J, Royer PJ, Evanno G, Lheriteau E, Ciron C, Salama A, at al. LIS1, a glyco-humanized swine polyclonal anti-lymphocyte globulin, as a novel induction treatment in solid organ transplantation. Front Immunol. 2023 Feb 16:14:1 137629.
• Umair M, Scheeren VFDC, Beitsma MM, Colleoni S, Galli C, Lazzari G, et al. In Vitro-Produced Equine Blastocysts Exhibit Greater Dispersal and Intermingling of Inner Cell Mass Cells than In Vivo Embryos. Int J Mol Sci. 2023 Jun 1;24(11):9619.
• Casós K, Llatjós R, Blasco-Lucas A, Kuguel SG, Sbraga F, Galli C, et al. Differential Immune Response to Bioprosthetic Heart Valve Tissues in the α1,3Galactosyltransferase-Knockout Mouse Model. Bioengineering (Basel). 2023 Jul 13;10(7):833.
• Hildebrandt TB, Holtze S, Colleoni S, Hermes R, Stejskal J, Lekolool I, et al. In vitro fertilization program in white rhinoceros. Reproduction. 2023 Oct 25;166(6):383-399.
• Porta-Sánchez A, Mazzanti A, Tarifa C, et al. Unexpected impairment of INa underpins reentrant arrhythmias in a knock-in swine model of Timothy syndrome. Nat Cardiovasc. Res. 2023;2(12):1291-1309.

2022

• Cho J, Kim G, Qamar AY, Fang X, Roy PK, Tanga BM, et al. Improved efficiencies in the generation of multigene-modified pigs by recloning and using sows as the recipient. Zygote. 2022 Feb;30(1):103-110.
• Senage T, Paul A, Le Tourneau T, Fellah-Hebia I, Vadori M, Bashir S, et al. The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration. Nat Med. 2022 Feb;28(2):283-294.
• Zywitza V, Rusha E, Shaposhnikov D, Ruiz-Orera J, Telugu N, Rishko V, et al. Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction. Sci Rep. 2022 Mar 8;12(1):3100.
• Biasetti P, Hildebrandt TB, Göritz F, Hermes R, Holtze S, Galli C, et al. Ethical Analysis of the Application of Assisted Reproduction Technologies in Biodiversity Conservation and the Case of White Rhinoceros (Ceratotherium simum) Ovum Pick-Up Procedures. Front Vet Sci. 2022 May 3:9:831675.
• Righi M, Morara S, Petrillo G, Perota A, Cagnotti G, Corona C. A Spatial Dispersion Approach Qualifies to Quantify Vascular Alterations in a Swine Amyotrophic Lateral Sclerosis Model. Medical Research Archives, [S.l.], v. 10, n. 9, sep. 2022. ISSN 2375-1924.
• Galiñanes M, Casós K, Blasco-Lucas A, Permanyer E, Máñez R, Le Tourneau T,et al. Oxidative Stress in Structural Valve Deterioration: A Longitudinal Clinical Study. Biomolecules. 2022 Oct 31;12(11):1606.
• Zywitza V, Frahm S, Krüger N, Weise A, Göritz F, Hermes R, et al. Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros. iScience. 2022 Oct 21;25(11):105414.
• Hayashi M, Zywitza V, Naitou Y, Hamazaki N, Goeritz F, Hermes R, et al. Robust induction of primordial germ cells of white rhinoceros on the brink of extinction. Sci Adv. 2022 Dec 9;8(49).

2021

• Vanhove B, Duvaux O, Rousse J, Royer PJ, Evanno G, Ciron C., et al. High neutralizing potency of swine glyco-humanized polyclonal antibodies against SARS-CoV-2. Eur J Immunol. 2021 Jun;51(6):1412-1422.
• Galli C, Lazzari G. Current applications of SCNT in advanced breeding and genome editing in livestock. Reproduction. 2021 Jun 11;162(1): F23-F32

2020

• Lazzari G, Colleoni S, Crotti G, Turini P, Fiorini G, Barandalla M, et al. Laboratory Production of Equine Embryos. Journal of Equine Veterinary Science. 2020 Jun; 89:103097.
• Jin C, Cherian RM, Liu J, Playà-Albinyana H, Galli C, Karlsson NG, Breimer ME, Holgersson J. Identification by mass spectrometry and immunoblotting of xenogeneic antigens in the N- and O-glycomes of porcine, bovine and equine heart tissues. Glycoconj J. 2020 Aug;37(4):485-498.

2019

• Reuven EM, Leviatan Ben-Arye S, Yu H, Duchi R, Perota A, Conchon S, et al. Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy. ACS nano. 2019.
• Perota A, Lagutina I, Duchi R, Zanfrini E, Lazzari G, Judor JP, et al. Generation of cattle knockout for galactose-alpha1,3-galactose and N-glycolylneuraminic acid antigens. Xenotransplantation. 2019:e12524.
• Hendriks WK, Colleoni S, Galli C, Paris D, Colenbrander B, Stout TAE. Mitochondrial DNA replication is initiated at blastocyst formation in equine embryos. Reprod Fertil Dev. 2019;31:570-8.
• Crociara P, Chieppa MN, Vallino Costassa E, Berrone E, Gallo M, Lo Faro M, et al. Motor neuron degeneration, severe myopathy and TDP-43 increase in a transgenic pig model of SOD1-linked familiar ALS. Neurobiology of disease. 2019;124:263-75.
• Claes A, Cuervo-Arango J, van den Broek J, Galli C, Colleoni S, Lazzari G, et al. Factors affecting the likelihood of pregnancy and embryonic loss after transfer of cryopreserved in vitro produced equine embryos. Equine Vet J. 2019 Jul;51(4):446-450.
• Perota A, Galli C. N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH). Front Immunol. 2019 Oct 15:10:2396.
• Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Arye S, et al. Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome. Xenotransplantation. 2019 Nov;26(6):e12535.

2018

• Trapani I, Perota A, Tiberi P, Colecchi L, Lagutina I, Duchi R, et al. Genome Editing to Generate a Pig Model of Stargardt Disease Type 1. Molecula Therapy. 2018;26:403-4.
• Scobie L, Galli C, Gianello P, Cozzi E, Schuurman HJ. Cellular xenotransplantation of animal cells into people: benefits and risk. Revue scientifique et technique (International Office of Epizootics). 2018;37:113-22.
• Quadalti C, Brunetti D, Lagutina I, Duchi R, Perota A, Lazzari G, et al. SURF1 knockout cloned pigs: Early onset of a severe lethal phenotype. Biochim Biophys Acta. 2018;1864:2131-42.
• Loi P, Galli C, Lazzari G, Matsukawa K, Fulka J, Jr., Goeritz F, et al. Development to term of sheep embryos reconstructed after inner cell mass/trophoblast exchange. J Reprod Dev. 2018;64:187-91.
• Linda S, Claire C, I. MN, Cesare G, Andrea P, Pierre G. Viral pathogens: What are they and do they matter? Xenotransplantation. 2018;25:e12412.
• Hildebrandt TB, Hermes R, Colleoni S, Diecke S, Holtze S, Renfree MB, et al. Embryos and embryonic stem cells from the white rhinoceros. Nat Commun. 2018;9:2589.
• Hendriks WK, Colleoni S, Galli C, Paris D, Colenbrander B, Stout TAE. Mitochondrial DNA replication is initiated at blastocyst formation in equine embryos. Reprod Fertil Dev. 2018.
• Galli C. UC Davis Transgenic Animal Research Conference XI (TARC XI). Transgenic Research. 2018;27:461-6.
• Claes A, Cuervo-Arango J, van den Broek J, Galli C, Colleoni S, Lazzari G, et al. Factors affecting the likelihood of pregnancy and embryonic loss after transfer of cryopreserved in vitro produced equine embryos. Equine Vet J. 2018.
• Barone A, Benktander J, Whiddon C, Jin C, Galli C, Teneberg S, et al. Glycosphingolipids of porcine, bovine, and equine pericardia as potential immune targets in bioprosthetic heart valve grafts. Xenotransplantation. 2018;25:e12406.

 

2017

• Salama A, Mosser M, Leveque X, Perota A, Judor JP, Danna C, et al. Neu5Gc and alpha1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs. Diabetes. 2017;66:987-93.
• Ruggeri E, DeLuca KF, Galli C, Lazzari G, DeLuca JG, Stokes JE, et al. Use of Confocal Microscopy to Evaluate Equine Zygote Development After Sperm Injection of Oocytes Matured In Vivo or In Vitro. Microsc Microanal. 2017;23:1197-206.
• Naso F, Stefanelli U, Buratto E, Lazzari G, Perota A, Galli C, et al. Alpha-Gal Inactivated Heart Valve Bioprostheses Exhibit an Anti-Calcification Propensity Similar to Knockout Tissues(). Tissue Eng Part A. 2017;23:1181-95.
• Mourad NI, Perota A, Xhema D, Galli C, Gianello P. Transgenic Expression of Glucagon-Like Peptide-1 (GLP-1) and Activated Muscarinic Receptor (M3R) Significantly Improves Pig Islet Secretory Function. Cell transplantation. 2017;26:901-11.
• Duisit J, Orlando G, Debluts D, Maistriaux L, Xhema D, de Bisthoven YJ, et al. Decellularization of the Porcine Ear Generates a Biocompatible, Nonimmunogenic Extracellular Matrix Platform for Face Subunit Bioengineering. Annals of surgery. 2017.
• C G. Achievements and unmet promises of assisted reproduction technologies in large animals: a personal perspective. Animal Reproduction. 2017;14:614-21.
• Barandalla M, Shi H, Xiao H, Colleoni S, Galli C, Lio P, et al. Global gene expression profiling and senescence biomarker analysis of hESC exposed to H2O2 induced non-cytotoxic oxidative stress. Stem Cell Res Ther. 2017;8:160.
• Barandalla M, Haucke E, Fischer B, Navarrete Santos A, Colleoni S, Galli C, et al. Comparative Analysis of AGE and RAGE Levels in Human Somatic and Embryonic Stem Cells under H2O2-Induced Noncytotoxic Oxidative Stress Conditions. Oxid Med Cell Longev. 2017;2017:4240136.
• Ramos-Ibeas P, Barandalla M, Colleoni S, Lazzari G. Pyruvate antioxidant roles in human fibroblasts and embryonic stem cells. Mol Cell Biochem. 2017 May;429(1-2):137-150. doi: 10.1007/s11010-017-2942-z. Epub 2017 Feb 28. PubMed PMID: 28247212.

 

2016

• Walter J, Colleoni S, Lazzari G, Fortes C, Grossmann J, Roschitzki B, et al. Developmental Competence of Equine Oocytes is Associated with Alterations in their Cumulus Proteome. Journal of Equine Veterinary Science. 2016;41:77-8.
• Saragusty J, Diecke S, Drukker M, Durrant B, Friedrich Ben-Nun I, Galli C, et al. Rewinding the process of mammalian extinction. Zoo Biol. 2016;35:280-92.
• Sanchez R, Herrera C, Blanco M, Rosati I, Lazzari G, Colleoni S, et al. In Vitro Production of Equine Embryos by Ovum Pick Up and Intracytoplasmic Sperm Injection in Young Mares. Journal of Equine Veterinary Science. 2016;41:77.
• Rubio A, Luoni M, Giannelli SG, Radice I, Iannielli A, Cancellieri C, et al. Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming. Sci Rep. 2016;6:37540.
• Reynard O, Jacquot F, Evanno G, Mai HL, Salama A, Martinet B, et al. Anti-EBOV GP IgGs Lacking alpha1-3-Galactose and Neu5Gc Prolong Survival and Decrease Blood Viral Load in EBOV-Infected Guinea Pigs. PLoS One. 2016;11:e0156775.
• Quadalti C, Galli C, Lazzari G. Development of an in vitro test battery for the screening of the receptor-mediated mechanism and the spindle-poison mode of action of estrogenic compounds. Environ Toxicol Pharmacol. 2016;48:245-52.
• Perota A, Lagutina I, Quadalti C, Lazzari G, Cozzi E, Galli C. The Applications of Genome Editing in Xenotransplantation. Journal of Genetics and Genomics. 2016;43:233-7.
• Galli C, Colleoni S, Duchi R, Lazzari G. Male Factors Affecting the Success of Equine In Vitro Embryo Production by Ovum Pickup-Intracytoplasmic Sperm Injection in a Clinical Setting. Journal of Equine Veterinary Science. 2016;43, Supplement:S6-S10.
• Galli C, Colleoni S, Claes A, Beitsma M, Deelen C, Necchi D, et al. Overnight shipping of equine oocytes from remote locations to an ART laboratory enables access to the flexibility of Ovum Pick Up-ICSI and embryo cryopreservation technologies. Journal of Equine Veterinary Science. 2016;41:82.
• Colleoni S, Lazzari G, Duchi R, Baca Castex C, Mari G, Lagutina I, et al. Fertilization and development of oocytes after ICSI with semen of stallions with different in vivo fertility. Journal of Equine Veterinary Science. 2016;32:408-9.
• Claes A, Galli C, Colleoni S, Necchi D, Lazzari G, Deelen C, et al. Factors influencing oocyte recovery and in-vitro production of equine embryos in a commercial OPU/ICSI program. Journal of Equine Veterinary Science. 2016;41:68-9.
• Butler JR, Martens GR, Estrada JL, Reyes LM, Ladowski JM, Galli C, et al. Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation. Transgenic Res. 2016.
• Buist M, Komatsu E, Lopez P, L. G, Bodnar E, Salama A, et al. Features of N-Glycosylation of Immunoglobulins from Knockout Pig Models J Anal Bioanal Tech. 2016;7.
• Barandalla M, Colleoni S, Lazzari G. Differential Response of Human Embryonic Stem and Somatic Cells to Non-Cytotoxic Hydrogen Peroxide Exposure: An Attempt to Model In Vitro the Effects of Oxidative Stress on the Early Embryo. Cell Dev Biol. 2016 Aug;5(2). pii: 177. Epub 2016 Aug 31. PubMed PMID: 27774366; PubMed Central PMCID: PMC5074058.

 

2015

• Tessaro I, Modina SC, Crotti G, Franciosi F, Colleoni S, Lodde V, et al. Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte fertilization test. Reprod Toxicol. 2015;51C:106-13.
• Ruggeri E, DeLuca KF, Galli C, Lazzari G, DeLuca JG, Carnevale EM. Cytoskeletal alterations associated with donor age and culture interval for equine oocytes and potential zygotes that failed to cleave after intracytoplasmic sperm injection. Reprod Fertil Dev. 2015;27:944-56.
• Paulis M, Castelli A, Susani L, Lizier M, Lagutina I, Focarelli ML, et al. Chromosome transplantation as a novel approach for correcting complex genomic disorders. Oncotarget. 2015;6:35218-30.
• Le Bas-Bernardet S, Tillou X, Branchereau J, Dilek N, Poirier N, Châtelais M, et al. Bortezomib, C1-Inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi-Transgenic GalT-KO Pig Kidney Xenografts in Baboons. American Journal of Transplantation. 2015;15:358-70.

 

2014

• Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Zagoura D, Bremer S, Sachinidis A, Lazzari G. A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system. Toxicol Lett. 2014 Sep 2;231(1):38-44. doi: 10.1016/j.toxlet.2014.08.023. [Epub ahead of print]
• Abeni F, Capelletti M, Terzano GM, Federici C, Speroni M, Petrera F, Dal Prà A, Galli C, Duchi R, Lazzari G, Pirlo G, Aleandri R. Plasma estrone sulfate, clinical biochemistry, and milk yield of dairy cows carrying a fetus from a bull or its clone. Theriogenology. 2014 Jul 23. pii: S0093-691X(14)00356-2. doi: 10.1016/j.theriogenology.2014.07.015. [Epub ahead of print]
• Vabres B, Le Bas-Bernardet S, Riochet D, Chérel Y, Minault D, Hervouet J, Ducournau Y, Moreau A, Daguin V, Coulon F, Pallier A, Brouard S, Robson SC, Nottle MB, Cowan PJ, Venturi E, Mermillod P, Brachet P, Galli C, Lagutina I, Duchi R, Bach JM, Blancho G, Soulillou JP, Vanhove B. hCTLA4-Ig transgene expression in keratocytes modulates rejection of corneal xenografts in a pig to non-human primate anterior lamellar keratoplasty model. Xenotransplantation. 2014 Jul 8. doi: 10.1111/xen.12107. [Epub ahead of print]
• Rossi B, Merlo B, Colleoni S, Iacono E, Tazzari PL, Ricci F, Lazzari G, Galli C. Isolation and in Vitro Characterization of Bovine Amniotic Fluid Derived Stem Cells at Different Trimesters of Pregnancy. Stem Cell Rev. 2014 Oct;10(5):712-24. doi: 10.1007/s12015-014-9525-0.
• Chieppa MN, Perota A, Corona C, Grindatto A, Lagutina I, Vallino Costassa E, Lazzari G, Colleoni S, Duchi R, Lucchini F, Caramelli M, Bendotti C, Galli C, Casalone C. Modeling Amyotrophic Lateral Sclerosis in hSOD1 Transgenic Swine. Neurodegener Dis. 2014;13(4):246-54. doi: 10.1159/000353472. Epub 2013 Oct 23.
• Galli C, Duchi R, Colleoni S, Lagutina I, Lazzari G. Ovum pick up, intracytoplasmic sperm injection and somatic cell nuclear transfer in cattle, buffalo and horses: from the research laboratory to clinical practice. Theriogenology. 2014 Jan 1;81(1):138-51.
• Galli C, Colleoni S, Turini P, Crotti G, Dieci C, Lodde V, Luciano AM, Lazzari G  Holding equine oocytes at room temperature for 18 hours prior to in vitro maturation maintains their developmental competence Journal of Equine Veterinary Science Volume 34, Issue 1 , Pages 174-175, January 2014
• Galli C, Lagutina I, Duchi R, Colleoni S, Lazzari G. Cloning of Equines. In: Cibelli J GJ, Wilmut I, Lanza M, West MD, Campbell KS, editor. Principles of Cloning. second edition ed. Amsterdam: Elsevier Academic Press; 2014. p. 287-97.

 

2013

• Busby SA, Crossan C, Godwin J, Petersen B, Galli C, Cozzi E,Takeuchi Y, Scobie L. Suggestions for the diagnosis and elimination of hepatitis E virus in pigs used for xenotransplantation. Xenotransplantation. 2013 May 7. doi: 10.1111/xen.12038
• Czernik M, Fidanza A, Sardi M, Galli C, Brunetti D, Malatesta D, Della Salda L, Matsukawa K, Ptak G, Loi P. Differentiation potential and GFP labeling of sheep bone marrow derived mesenchymal stem cells. J Cell Biochem. 2013 Jan;114(1):134-43.
• Dieci C, Lodde V, Franciosi F, Lagutina I, Tessaro I, Modina SC, Albertini DF, Lazzari G, Galli C, Luciano AM.The effect of cilostamide on gap junction communication dynamics, chromatin remodeling, and competence acquisition in pig oocytes following parthenogenetic activation and nuclear transfer. Biol Reprod. 2013 Sep 27;89(3):68. doi: 10.1095/biolreprod.113.110577. Print 2013 Sep.
• Galli C, Colleoni S, Duchi R, Lagutina I, Lazzari G. Equine Assisted Reproduction and Embryo Technologies. Anim. Reprod., v.10, n.3, p.334-343, Jul./Sept. 2013
• Hall V, Hinrichs K, Lazzari G, Betts DH, Hyttel P. Early embryonic development, assisted reproductive technologies, and pluripotent stem cell biology in domestic mammals. Vet J. 2013 Aug;197(2):128-42. doi: 10.1016/j.tvjl.2013.05.026. Epub 2013 Jun 27. Review.
• Lagutina I, Fulka H, Lazzari G, Galli C Interspecies somatic cell nuclear transfer: advancements and problems. Cell Reprogram. 2013 Oct;15(5):374-84. doi: 10.1089/cell.2013.0036. Epub 2013 Sep 13.
• Lauri A, Lazzari G, Galli C, Lagutina I, Genzini E, Braga F, Mariani P, Williams JL. Assessment of MDA efficiency for genotyping using cloned embryo biopsies. Genomics.2013 Jan;101(1):24-9.
• Lazzari G, Colleoni S, Galli C. Derivation of neural precursors from bovine preimplantation embryos. Methods Mol Biol. 2013;1074:199-207. doi: 10.1007/978-1-62703-628-3_15.
• Naso F, Gandaglia A, Bottio T, Tarzia V, Nottle MB, d’Apice AJ, Cowan PJ, Cozzi E, Galli C, Lagutina I, Lazzari G, Iop L, Spina M, Gerosa G.  First quantification of alpha-Gal epitope in current glutaraldehyde-fixed heart valve bioprostheses. Xenotransplantation. 2013 Jul-Aug;20(4):252-61. doi: 10.1111/xen.12044. Epub 2013 Jul 19.
• Puglisi R, Cambuli C, Capoferri R, Giannino L, Lukaj A, Duchi R, Lazzari G, Galli C, Feligini M, Galli A, Bongioni G. Differential gene expression in cumulus oocyte complexes collected by ovum pick up from repeat breeder and normally fertile Holstein Friesian heifers. Anim Reprod Sci. 2013 Sep;141(1-2):26-33. doi: 10.1016/j.anireprosci.2013.07.003. Epub 2013 Jul 17.
• Schubert T, Poilvache H, Galli C, Gianello P, Dufrane D. Galactosyl-knock-out engineered pig as a xenogenic donor source of adipose MSCs for bone regeneration. Biomaterials. 2013;34(13):3279-89.
• Spiezia L, Boldrin M, Radu C, Bulato C, Bertini D, Bon M, Campello E, Vadori M, Galli C, Gavasso S, Nottle MB, Cowan PJ, Cozzi E, Simioni P Thromboelastographic evaluation of coagulative profiles in pig-to-monkey kidney xenotransplantation. Xenotransplantation. 2013;20(2):89-99.

 

2012

• Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Sachinidis A, Lazzari G.Characterisation of a neural teratogenicity assay based on human ESCs differentiation following exposure to valproic acid. Curr Med Chem. 2012 Dec 1;19(35):6065-71.
• Galli C, Lagutina I, Perota A, Colleoni S, Duchi R, Lucchini F, Lazzari G.Somatic cell nuclear transfer and transgenesis in large animals: current and future insights. Reprod Domest Anim. 2012 Jun;47 Suppl 3:2-11.

 

2011

• Chatelais M, Devallière J, Galli C, Charreau B. Gene transfer of the adaptor Lnk (SH2B3) prevents porcine endothelial cell activation and apoptosis: implication for xenograft’s cytoprotection. Xenotransplantation. 2011 Mar;18(2):108-20.
• Colleoni S, Lagutina I, Lazzari G, Rodriguez-Martinez H, Galli C, Morrell JM. New Methods for Selecting Stallion Spermatozoa for Assisted Reproduction  Journal of Equine Veterinary Science, Volume 31, Issue 9, September 2011, Pages 536-541.
• Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Sachinidis A, Lazzari G. Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic Acid exposure. Toxicol Sci. 2011 Dec;124(2):370-7.
• Lagutina I, Zakhartchenko V, Fulka H, Colleoni S, Wolf E, Fulka J, Lazzari G, Galli C. Formation of nucleoli in interspecies nuclear transfer embryos derived from bovine, porcine and rabbit oocytes and nuclear donor cells of various species. Reproduction. 2011 Jan 14.
• Lazzari G, Colleoni S, Duchi R, Galli A, Houghton FD, Galli C. Embryonic genotype and inbreeding affect preimplantation development in cattle. Reproduction. 2011 May;141(5):625-632.
• Le Bas-Bernardet S, Tillou X, Poirier N, Dilek N, Chatelais M, Devallière J, Charreau B, Minault D, Hervouet J, Renaudin K, Crossan C, Scobie L, Cowan PJ, d’Apice AJ, Galli C, Cozzi E, Soulillou JP, Vanhove B, Blancho G. Xenotransplantation of Galactosyl-Transferase Knockout, CD55, CD59, CD39, and Fucosyl-Transferase Transgenic Pig Kidneys Into Baboons. Transplant Proc. 2011 Nov;43(9):3426-30.
• Lorenzetti S, Altieri I, Arabi S, Balduzzi D, Bechi N, Cordelli E, Galli C, Ietta F, Modina SC, Narciso L, Pacchierotti F, Villani P, Galli A, Lazzari G, Luciano AM, Paulesu L, Spanò M, Mantovani A. Innovative non-animal testing strategies for reproductive toxicology: the contribution of Italian partners within the EU project ReProTect. Ann Ist Super Sanita. 2011;47(4):429-44. Review.

 

2010

• Colleoni S, Galli C, Giannelli SG, Armentero MT, Blandini F, Broccoli V, Lazzari G. Long-term culture and differentiation of CNS precursors derived from anterior human neural rosettes following exposure to ventralizing factors. Exp Cell Res. 2010 Apr.
• De Lorenzi L, Molteni L, Zannotti M, Galli C, Parma P. (2010). X trisomy in a sterile mare. Equine Veterinary Journal. vol. 42, pp. 469 – 470.
• Fahrenkrug SC,  Blake A,  Carlson DF,  Doran T,  Van Eenennaam A,  Faber D, Galli C, Gao Q,  Hackett PB,  Li N, Maga EA,  Muir WM,  Murray JD, Shi D, Stotish R,  Sullivan E,  Taylor JF,  Walton M,  Wheeler M, Whitelaw B and  Glenn BP “Precision genetics for complex objectives in animal agriculture” J Anim Sci 2010.88:2530-2539.
• Galli C, Perota A, Brunetti D, Lagutina I, Lazzari G, Lucchini F. “Genetic engineering including superseding microinjection: new ways to make GM pigs“. Xenotransplantation 2010; 17: 397–410.
• Lagutina I, Fulka H, Brevini TA, Antonini S, Brunetti D, Colleoni S, Gandolfi F, Lazzari G, Fulka J Jr, Galli C. Development, embryonic genome activity and mitochondrial characteristics of bovine-pig inter-family nuclear transfer embryos. Reproduction. 2010 Aug. 140(2):273-85.
• Lazzari G, Colleoni S, Lagutina I, Crotti G, Turini P, Tessaro I, Brunetti D, Duchi R, Galli C. Short-term and long-term effects of embryo culture in the surrogate sheep oviduct versus in vitro culture for different domestic species. Theriogenology. 2010  Apr 1;73(6):748-57.
• Luciano AM, Franciosi F, Lodde V, Corbani D, Lazzari G, Crotti G, Galli C, Pellizzer C, Bremer S, Weimer M, Modina SC.Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte maturation (IVM) test within ReProTect.Reprod Toxicol. 2010 Aug;30(1):81-8
• Pisani LF, Pennarossa G, Papasso Brambilla E, Rahman MM, Lazzari G, Zecconi A, Brevini TA, Gandolfi F. Newborn pig ovarian tissue xenografted  into Severe Combined Immunodeficient (SCID) mice acquires limited responsiveness to gonadotropins.Theriogenology.2010 Sep 1;74(4):557-62.
• Schenk B, Weimer M, Bremer S, van der Burg B, Cortvrindt R, Freyberger A, Lazzari G, Pellizzer C, Piersma A, Schäfer WR, Seiler A, Witters H, Schwarz M. The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants. Reprod Toxicol. 2010 Aug;30(1):200-18

 

2009

• Colleoni S, Bottani E, Tessaro I, Mari G, Merlo B, Romagnoli N, Spadari A, Galli C, Lazzari G. Isolation, growth and differentiation of equine mesenchymal stem cells: effect of donor, source, amount of tissue and supplementation with basic fibroblast growth factor. Vet Res Commun. 2009 Dec;33(8):811-21.
• Sachs DH,  Galli C  Genetic manipulation in pigs Current Opinion in Organ Transplantation 2009, 14:148–153.
• Smits K, Goossens K, Van Soom A, Govaere J, Hoogewijs M, Vanhaesebrouck E, Galli C, Colleoni S, Vandesompele J, Peelman L. Selection of reference genes for quantitative real-time PCR in equine in vivo and fresh and frozen-thawed in vitro blastocysts. BMC Res Notes. 2009 Dec 11;2:246.
• Tharasanit T, Colleoni S, Galli C, Colenbrander B, Stout TA. Protective effects of the cumulus-corona radiata complex during vitrification of horse oocytes. Reproduction. 2009 Mar;137(3):391-401. doi: 10.1530/REP-08-0333. Epub 2008 Dec 10.

 

2008

• Brunetti D, Perota A, Lagutina I, Colleoni S, Duchi R, Calabrese F, Seveso M, Cozzi E, Lazzari G, Lucchini F, Galli C. Transgene Expression of Green Fluorescent Protein and Germ Line Transmission in Cloned Pigs Derived from In Vitro Transfected Adult Fibroblasts. Cloning Stem Cells 2008 Dec;10(4):409-19.
• Cruz NT, Wilson KJ, Cooney MA, Tecirlioglu RT, Lagutina I, Galli C, Holland MK, French AJ. Putative imprinted gene expression in uniparental bovine embryo models. Reprod Fertil Dev 2008;20: 589-597. Full abstract.
• Fulka J, Jr., Fulka H, St John J, Galli C, Lazzari G, Lagutina I, Fulka J, Loi P. Cybrid human embryos – warranting opportunities to augment embryonic stem cell research. Trends Biotechnol 2008 Sep;26(9):469-74.
• Galli C, Lazzari G. The manipulation of gametes and embryos in farm animals. Reprod Domest Anim 2008;43 Suppl 2: 1-7.
• Galli C, Lagutina I, Duchi R, Colleoni S, Lazzari G. Somatic cell nuclear transfer in horses. Reprod Domest Anim 2008;43 Suppl 2: 331-337. Full text.
• Lazzari G, Tessaro I, Crotti G, Galli C, Hoffmann S, Bremer S, Pellizzer C. Development of an in vitro test battery for assessing chemical effects on bovine germ cells under the ReProTect umbrella. Toxicol Appl Pharmacol. 2008; 233:360-70.
• Nowak-Imialek M, Wrenzycki C, Herrmann D, Lucas-Hahn A, Lagutina I, Lemme E, Lazzari G, Galli C, Niemann H. Messenger RNA expression patterns of histone-associated genes in bovine preimplantation embryos derived from different origins. Mol Reprod Dev 2008;75: 731-743.
• Santoni de Sio FR, Gritti A, Cascio P, Neri M, Sampaolesi M, Galli C, Luban J, Naldini L. Lentiviral Vector Gene Transfer is Limited by the Proteasome at Post-Entry Steps in Various Types of Stem Cells. Stem Cells 2008 Aug;26(8):2142-52.

 

2007

• Brown BD, Gentner B, Cantore A, Colleoni S, Amendola M, Zingale A, Baccarini A, Lazzari G, Galli C, Naldini L. Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state. Nat Biotechnol. 2007 Dec;25(12):1457-1467. Epub 2007 Nov 16.
• Colleoni S, Barbacini S, Necchi Denis, Duchi R. Lazzari G, Galli C. Clinical application of ovum pick-up, intracytoplasmic sperm injection and embryo culture in equine practice. Proceedings of the American Association for Equine Practitioners (AAEP), vol 53, 554-559 2007.
• Galli C, Colleoni, S, Duchi, R, Lagutina, I, Lazzari, G. Developmental competence of equine oocytes and embryos obtained by in vitro procedures ranging from in vitro maturation and ICSI to embryo culture, cryopreservation and somatic cell nuclear transfer.Anim Reprod Sci. 2007, 98: 39-55.
• Lagutina I, Lazzari G, Duchi R, Turini P, Tessaro I, Brunetti D, Colleoni S, Crotti G, Galli C. Comparative aspects of somatic cell nuclear transfer with conventional and zona-free method in cattle, horse, pig and sheep.Theriogenology. 2007 Jan 1;67(1):90-8. Epub 2006 Nov 1. Review.
• Loi P, Galli C, Ptak G. Cloning of endangered mammalian species: any progress? Trends Biotechnol. 2007 May;25(5):195-200.Epub 2007 Mar 26.
• Lombardo A, Beausejour CM, Genovese P, Colleoni S, Lee Y-L,Kim KA, Ando D, Urnov F, Galli C, Gregory PD, Holmes MC, Naldini L. Gene editing and site-specific gene additino in human stem cells using designed zinc finger nucleases and integrase detective lentiviral vector delivery. Nat Biotechnol. 2007 Nov;25(11):1298-306. Epub 2007 Oct 28.

 

2006

• Lagutina I, Lazzari G, Duchi R, Turini P, Tessaro I, Brunetti D, Colleoni S, Crotti G, Galli C. Comparative aspects of somatic cell nuclear transfer with conventional and zona-free method in cattle, horse, pig and sheep. Theriogenology. 2007 Jan 1;67(1):90-8. Epub 2006 Nov 1.
• Lagutina, I, Lazzari, G. Galli, C. Birth of cloned pigs from zona-free nuclear transfer embryos developed in vitro to blastocyst before transfer. Cloning and Stem Cells Dec 2006, Vol. 8, No. 4: 283-293.
• Lazzari, G., Colleoni, S., Giannelli, S. G., Brunetti, D., Colombo, E., Lagutina, I., Galli, C., and Broccoli, V. Direct derivation of neural rosettes from cloned bovine blastocysts: a model of early neurulation events and neural crest specification in vitro. Stem Cells. 2006 Nov;24(11):2514-21. Epub 2006 Aug 24
• Puglisi R, Vanni R, Galli A, Balduzzi D, Parati K, Bongioni G, Crotti G, Duchi R, Galli C, Lazzari G, Aleandri R. In vitro fertilisation with frozen-thawed bovine sperm sexed by flow cytometry and validated for accuracy by real-time PCR. Reproduction. 2006 Sep;132(3):519-26.
• Tharasanit T, Colleoni S, Lazzari G, Colenbrander B, Galli C, Stout TA. Effect of cumulus morphology and maturation stage on the cryopreservability of equine oocytes. Reproduction. 2006 Nov;132(5):759-69.

 

2005

• Bremer S, Balduzzi D, Cortvrindt R, Daston G, Eletti B, Galli A, Huhtaniemi I, Laws S, Lazzari G, Liminga U, Smitz J, Spano M, Themmen A, Tilloy A, Waalkens-Behrends I. The effects of chemicals on mammalian fertility. The report and recommendations of ECVAM Workshop 53–the first strategic workshop of the EU ReProTect Project. Altern Lab Anim. 2005 Aug;33(4):391-416.. Full text.
• Colleoni S, Donofrio G, Lagutina I, Duchi R, Galli C, Lazzari G. Establishment, differentiation, electroporation, viral transduction, and nuclear transfer of bovine and porcine mesenchymal stem cells. Cloning Stem Cells. 2005;7(3):154-66.
• Donofrio G, Colleoni S, Galli C, Lazzari G, Cavirani S, Flammini CF. Susceptibility of bovine mesenchymal stem cells to bovine herpesvirus 4. J Virol Methods. 2005 Aug;127(2):168-70.
• Lagutina I, Lazzari G, Duchi R, Colleoni S, Ponderato N, Turini P, Crotti G, Galli C. Somatic cell nuclear transfer in horses: effect of oocyte morphology, embryo reconstruction method and donor cell type. Reproduction. 2005 Oct;130(4):559-567.
• Rambags BP, Krijtenburg PJ, Drie HF, Lazzari G, Galli C, Pearson PL, Colenbrander B, Stout TA. Numerical chromosomal abnormalities in equine embryos produced in vivo and in vitro. Mol Reprod Dev. 2005 Sep;72(1):77-87.
• Luciano AM, Lodde V, Beretta MS, Colleoni S, Lauria A, Modina S. Developmental capability of denuded bovine oocyte in a co-culture system with intact cumulus-oocyte complexes: role of cumulus cells, cyclic adenosine 3′,5′-monophosphate, and glutathione. Mol Reprod Dev 2005; 71: 389-397.

 

2004

• Beaujean N, Taylor JE, McGarry M, Gardner JO, Wilmut I, Loi P, Ptak G, Galli C, Lazzari G, Bird A, Young LE, Meehan RR. The effect of interspecific oocytes on demethylation of sperm DNA. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7636-40.
• Brevini TA, Cillo F, Colleoni S, Lazzari G, Galli C, Gandolfi F. Expression pattern of the maternal factor zygote arrest 1 (Zar1) in bovine tissues, oocytes, and embryos. Mol Reprod Dev 2004; 69: 375-380.
• Donnay I, Faerge I, Grondahl C, Verhaeghe B, Sayoud H, Ponderato N, Galli C, Lazzari G. Effect of prematuration, meiosis activating sterol and enriched maturation medium on the nuclear maturation and competence to development of calf oocytes. Theriogenology 2004; 62: 1093-1107.
• Galli C, Duchi R, Lagutina I, Lazzari G. A European perspective on animal cloning and government regulation. IEEE Eng Med Biol Mag 2004; 23: 52-54.
• Galli C, Duchi R, Crotti G, Turini P, Ponderato N, Colleoni S, Lagutina I, Lazzari G. Production and quality of bovine oocytes and embryos. Vet Res Commun. 2004 Aug;28 Suppl 1:121-6. Full text.
• Heyman Y, Richard C, Rodriguez-Martinez H, Lazzari G, Chavatte-Palmer P, Vignon X, Galli C. Zootechnical performance of cloned cattle and offspring: preliminary results. Cloning Stem Cells 2004; 6: 111-120.
• Lagutina I, Lazzari G, Duchi R, Galli C. Developmental Potential of Bovine Androgenetic and Parthenogenetic Embryos: A Comparative Study. Biol Reprod. 2004 Feb;70(2):400-5. Epub 2003 Oct 15.
• Panelli S, Damiani G, Galli C, Sgaramella V. Rearranged genomes of bovine blood cells can allow the development of clones till late fetal stages; but rare unrearranged genomes have greater potential and lead to adulthood. Gene 2004; 334: 99-103.

 

2003

• Donofrio G, Galli C, Lazzari G, van Santen VL, Cavirani S. Flammini CF. (2003). Interaction of a green recombinant bovine herpesvirus 4 with in vitro produced bovine embryos. Vet. Res. Communications, 27, 415-424.
• Galli C, Lagutina I, Lazzari G. (2003). Introduction to cloning by nuclear transplantation. Cloning & Stem Cells, vol 5 n4, 223-232.
• Galli C. (2003). L’opinione pubblica tra scienza e pregiudizio. Bioetica, XI, n 3: 421-426.
• Galli C, Lagutina I, Crotti C, Colleoni S, Turini P, Ponderato N, Duchi R, Lazzari G. Pregnancy: a cloned horse born to its dam twin. Nature. 2003 Aug 7;424(6949):635.
• Galli C, Vassiliev I, Lagutina I, Galli A and  Lazzari G. (2003) Bovine embryo development following ICSI: effect of activation, sperm capacitation and pre-treatment with dithiothreitol. Theriogeneology 60 (8); 1467-1480
• Galli C, Duchi R, Crotti G, Ponderato N, Colleoni S, Lagutina I, Lazzari G. (2003). Bovine embryo technologies. Theriogenology, 59, 599-616.
• Miller DJ, Eckert JJ, Lazzari G, Duranthon-Richoux V, Sreenan J, Morris D, Galli C, Renard JP, Fleming TP. Tight Junction Messenger RNA Expression Levels in Bovine Embryos are Dependent upon the Ability to Compact and In Vitro Culture Methods.Biol Reprod. 2003 Apr;68(4):1394-402.
• Tremoleda JL, Stout TA, Lagutina I, Lazzari G, Bevers MM, Colenbrander B, Galli C. Effects of in vitro production on horse embryo morphology, cytoskeletal characteristics, and blastocyst capsule formation. Biol Reprod. 2003 Dec;69(6):1895-906. Epub 2003 Aug 06.

 

2002

• Galli C, Crotti G, Turini P, Duchi R, Mari G, Zavaglia G, Duchamp G, Daels P, Lazzari G. (2002). Frozen-thawed embryos produced by Ovum Pick Up and ICSI are capable to establish pregnancies in the horse. Theriogenology, 58, 713-715.
• Galli C, Lagutina I, Vassiliev I, Duchi R, Lazzari G. Comparison of microinjection (piezo-electric) and cell fusion for nuclear transfer success with different cell types in cattle. Cloning Stem Cells 2002;4(3):189-96.
• Lagutina I, Ponderato N, Lazzari G, Galli C. (2002). Kinetics of oocyte maturation and subsequent development of IVF, parthenogenetic and NT bovine embryos after meiotic inhibition with rescovitine. Cloning Stem Cells. 2002;4(2):113-119.
• Lazzari G, Crotti G, Turini P, Duchi R, Mari G, Zavaglia G, Barbacini S, Galli C. (2002). Equine embryos at the compacted morula and blastocyst stage can be obtained by intracytoplasmic sperm injection (ICSI) of in vitro matured oocytes with frozen-thawed spermatozoa from semen of different fertilities. Theriogenology, 58, 709-712.
• Lazzari G, Wrenzychi C, Hermann D, Duchi R, Kruip T, Niemann H, Galli C. Cellular and molecular deviations in bovine in vitro produced embryos are related to the large offspring syndrome. Biol. Reprod., 2002 Sep;67(3):767-75.
• Ponderato N, Crotti G, Turini P, Duchi R, Galli C, Lazzari G. Embryonic and foetal development of bovine oocytes treated with a combination of butyrolactone i and roscovitine in an enriched medium prior to ivm and ivf. Mol. Reprod. Dev., 2002 Aug;62(4):513-8.

 

2001

• Galli C, Crotti G, Notari C, Turini P, Duchi R and Lazzari G. (2001). Embryo production by ovum pick up from live donors. Theriogenology, 55: 1341-1357.
• Galli C, Lazzari G. Animal cloning experiments still banned in Italy. Nat Med. 2001 Jul;7(7):753.
• Ponderato N, Lagutina I, Crotti G, Turini P, Galli C, Lazzari G. (2001). Bovine oocytes treated prior to in vitro maturation with a combination of butyrolactone I and roscovitine at low doses maintain a normal developmental capacity. Mol. Reprod. Dev. 60:579-585

 

2000

•  Iwasaki S, Campbell KHS,  Galli C, Akiyama K &  Iwasaki S (2000). Production of Live Calves Derived from Embryonic Stem-Like Cells Aggregated with Tetraploid Embryos.Biol. Reprod. 62, 470-475.
• Navarrete Santos A, Augustin R, Lazzari G, Galli C,  Sreenan JM and Fischer B. (2000). The insulin-dependent glucose transporter isoform 4 is expressed in bovine blastocysts.Bioch. Bioph. Res. Comm. 271, 753-760.

 

1999

• Galli C, Duchi R, Moor R.M. and Lazzari G. (1999). Mammalian leukocytes contain all the genetic information necessary for the development of a new individual. Cloning 1: 161-170.
• van Eijk M.J.T. ,  van Rooijen  M.A.,  Modina S., Scesi L. ,  Folkers G., . van Tol H.T.A, Bevers M.M. ,  Fisher S.R.,  Lewin H.A., Rakacolli D.,  Gall C.,  de Vaureix C.,  Trounson A.O., Mummery C.L. , and  Gandolfi F.. (1999). Molecular Cloning, Genetic Mapping, and Developmental Expression of Bovine POU5F1. Biol. Reprod. 60: 1093-1103.

 

1996

• Galli, C. & Lazzari, G. (1996) Practical aspects of IVM/IVF in cattle. Animal Reprod. Sci. 42, 371-379.

 

1994

• Galli, C., Lazzari, G., Flechon, J-E & Moor, R.M. (1994). Embryonic stem cells in farm animals. Zygote 2: 385-389.
• Lazzari G., Galli C. & Moor R.M. (1994). Functional changes in the somatic and germinal compartments during follicle growth in pigs. Animal Reprod. Sci. 35,119-130.

 

1992

• Lazzari G, Galli C, Moor RM. (1992). Centrifugal elutriation of porcine oocytes isolated from the ovaries of newborn piglets. Anal Biochem. 1992 Jan;200(1):31-5.
• Moor, R. M., Sun, F.Z. & Galli, C. (1992). Reconstruction of ungulate embryos by nuclear transplantation.Animal Reprod. Sci. 28, 423-431